A case of ectopic adrenocorticotropic hormone syndrome caused by thymoma.
10.11817/j.issn.1672-7347.2019.180371
- Author:
Jianhua LIU
1
;
Baiyun ZHONG
1
;
Dongmei ZHANG
2
Author Information
1. Department of Clinical Laboratory, Xiangya Hospital, Central South University, Changsha 410008, China.
2. Department of Endocrinology, Xiangya Hospital, Central South University, Changsha 410008, China.
- Publication Type:Case Reports
- MeSH:
ACTH Syndrome, Ectopic;
Adrenocorticotropic Hormone;
Cushing Syndrome;
Female;
Humans;
Thymoma;
Thymus Neoplasms
- From:
Journal of Central South University(Medical Sciences)
2019;44(11):1316-1320
- CountryChina
- Language:Chinese
-
Abstract:
Cushing's syndrome is a clinically common type of clinical syndrome caused by excessive glucocorticoids. It can be divided into adrenocorticotropic-dependent and independent types according to its etiology. A female patient with Cushing's syndrome is reported to have a clinical manifestation of mild full moon face, masculinization of androgen increase, deeper skin color, elevated blood pressure, and pulmonary infection. The cause is unknown. Radiographic examination indicated that pituitary tumor and adrenal tumors did not exist. Chest enhancement CT examination revealed that the lesion was in the thymus. Thoracoscopy was performed to remove the tumor. Since wound infection occurred after operation, a variety of antibiotics were used for anti-infective treatment, and the wound gradually healed. After 21 months of follow-up, the above symptoms disappeared completely and the prognosis was good in the near future. Postoperative pathological diagnosis was thymic neuroendocrine carcinoma. This is a typical case that the thymoma ectopically secrets adrenocorticotropic hormone, which leads to Cushing's syndrome, referring to ectopic adrenocorticotropic hormone syndrome.
