End-stage renal disease and pulmonary hypertension.
10.11817/j.issn.1672-7347.2019.180799
- Author:
Bin SHENG
1
;
Tengteng ZHU
1
;
Jiang LI
1
Author Information
1. Department of Cardiology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
- Publication Type:Journal Article
- MeSH:
Heart Failure;
Humans;
Hypertension, Pulmonary;
Kidney Failure, Chronic;
Renal Dialysis;
Risk Factors
- From:
Journal of Central South University(Medical Sciences)
2019;44(12):1419-1422
- CountryChina
- Language:Chinese
-
Abstract:
Pulmonary hypertension (PH) is a common complication in patients with end-stage renal disease (ESRD), especially in patients with hemodialysis (HD). Poor prognosis can eventually lead to right heart failure and even death. PH is an independent risk factor for increased mortality in ESRD patients. We should pay attention to these patients in clinic for early detection, prevention and treatment. The pathogenesis of PH in ESRD patients is still unclear so far, which might be related to the increase of pulmonary vascular resistance, pulmonary blood flow, and pulmonary arterial wedge pressure. In addition, the presence of risk factors can promote the development of PH, such as chronic hypoxia, vascular calcification, and inflammation.
