Biological function of protein tyrosine phosphatase H-type receptor and its progress in tumor.
10.11817/j.issn.1672-7347.2020.180612
- Author:
Zhengxi HE
1
;
Jun SU
2
;
Qing LIU
2
;
Zihua CHEN
3
;
Liangfang SHEN
1
;
Haoyu LI
2
Author Information
1. Department of Oncology, Xiangya Hospital, Central South University, Changsha 410008, China.
2. Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha 410008, China.
3. Department of General Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
- Publication Type:Journal Article
- Keywords:
biological function;
protein tyrosine phosphatase H-type receptor;
tumor
- MeSH:
Humans;
Phosphorylation;
Protein Tyrosine Phosphatases;
Proteins;
Stomach Neoplasms;
Tyrosine
- From:
Journal of Central South University(Medical Sciences)
2020;45(1):61-67
- CountryChina
- Language:English
-
Abstract:
Protein tyrosine phosphatase H-type receptor (PTPRH) gene encodes a gastric cancer associated protein, which exerts its biological function through tyrosine phosphorylation in the post-translational COOH- terminal region. PTPRH is abnormally expressed in a variety of tumors, and its biological function is closely related to the occurrence, development and prognosis of tumors.
