Factors associated with failure of eradication.
10.11817/j.issn.1672-7347.2020.180730
- Author:
Lei GU
1
;
Huixiang YANG
1
Author Information
1. Department of Gastroenterology, Xiangya Hospital, Central South University, Changsha 410008, China.
- Publication Type:Journal Article
- Keywords:
Helicobacter pylori;
antibiotic resistance;
compliance;
eradication failure
- MeSH:
Gastric Mucosa;
Gastritis;
Helicobacter Infections;
Helicobacter pylori;
Humans
- From:
Journal of Central South University(Medical Sciences)
2020;45(1):79-84
- CountryChina
- Language:English
-
Abstract:
() infection is closely related to chronic active gastritis, peptic ulcer, mucosa-associated lymphoid tissue (MALT) lymphoma, and gastric cancer, and is also associated with some parenteral diseases. Eradication of can significantly improve gastric mucosal inflammatory response, prevent or delay gastric mucosal atrophy, intestinal metaplasia and its development, partially reverse atrophy, and reduce the risk of gastric cancer in varying degrees. In recent years, the eradication failure rate has increased. There are many reasons for the failure of eradication. Previous studies have suggested that resistance to antibiotics is the main cause of eradication failure, but recent studies have found that poor compliance is the main reason.