A case of blastic plasmacytoid dendritic cell neoplasm
- VernacularTitle:母细胞性浆细胞样树突状细胞瘤一例报告
- Author:
Hai-yue NIU
1
Author Information
1. Department of Hematology, Tianjin Medical University General Hospital, Tianjin 300052, China
- Publication Type:Journal Article
- Keywords:
hematologic neoplasms;
leukemia, myeloid, acute;
blastic plasmacytoid dendritic cell neoplasm;
diagnosis;
treatment
- From:
Tianjin Medical Journal
2018;46(8):828-831
- CountryChina
- Language:Chinese
-
Abstract:
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematopoietic neoplasm with high
malignancy and rapid progression. BPDCN is sensitive to chemotherapy, but it is prone to relapse and drug resistance, and
the survival time is short. We report a case of BPDCN hospitalized in our department. In this case, the skin lesions were the
first manifestation. The diagnosis of BPDCN was confirmed by the skin biopsy. Initially, this patient was sensitive to the
lymphoma chemotherapy but the disease relapsed quickly, spreading to the lungs and mediastinum. Then, we treated the
patient with myeloid regimen, which was no efficacy. The patient eventually died with an overall survival of 17 months.
