The interpretation of diagnostic criteria for myelodysplastic syndromes (2017)

VernacularTitle:骨髓增生异常综合征最低诊断标准（2017）解读
Author: Hua-quan WANG ¹
Author Information

1. Department of Hematology, Tianjin Medical University General Hospital, Tianjin 300052, China
Publication Type:Journal Article
Keywords: myelodysplastic syndromes; diagnosis; pre-MDS conditions
From: Tianjin Medical Journal 2018;46(8):811-814
CountryChina
Language:Chinese
Abstract: Myelodysplastic syndromes (MDS) comprises a heterogeneous group of myeloid clonal neoplasms characterized by peripheral cytopenia, dysplasia and a variable clinical course with about 30% risk to transform to secondary acute myeloid leukemia (AML). In the past 15 years, diagnostic evaluations, prognostication and treatment of MDS have improved substantially. However, with the discovery of molecular markers and advent of novel targeted therapies, new challenges have emerged in the complex field of MDS. We will summarize the proposed criteria for a classification of pre- MDS conditions as well as a proposed update for minimal diagnostic criteria of MDS in the present article.