Precision diagnosis and therapy of myelodysplastic syndrome based on disease nature and our facility
- VernacularTitle:从疾病本质出发，结合我国实际，精准诊治 骨髓增生异常综合征
- Author:
Zong-hong SHAO
1
;
Hua-quan WANG
Author Information
1. Department of Hematology, Tianjin Medical University General Hospital, Tianjin 300052, China
- Publication Type:Journal Article
- Keywords:
myelodysplastic syndromes;
diagnosis;
therapy;
pathogenesis
- From:
Tianjin Medical Journal
2018;46(8):785-788
- CountryChina
- Language:Chinese
-
Abstract:
The essence of myelodysplastic syndrome (MDS) is a malignant clonal bone marrow myeloid neoplasm. Both
basic researches and clinical studies should firmly grasp this essence of MDS and should not be interferenced by
confounding factors. Comprehensive diagnosis can improve the accuracy of MDS diagnosis by multiple indicators that reflect
the malignant nature, such as cell dysplasia, function abnormalities, cytogenetic changes and gene mutations. The therapy of
MDS should also eradicate the MDS clone, change the disease progression, stimulating normal hematopoiesis, prolong the
survival and improve the quality of life.
