Topical application of clobetasol propionate cream in the treatment of phimosis in prepubertal children: A report of 237cases.
- Author:
Yan-Lin WEN
1
;
An-Guo WANG
1
;
Zong-Ping ZHANG
1
;
Ji WU
1
;
Tao JIANG
1
Author Information
1. The Second School of Clinical Medicine/Department of Urology, Nanchong Central Hospital, North Sichuan Medical College, Nanchong, Sichuan 637000, China.
- Publication Type:Journal Article
- Keywords:
child;
phimosis;
steroid;
clobetasol propionate cream
- MeSH:
Administration, Topical;
Adolescent;
Anti-Inflammatory Agents;
administration & dosage;
Child;
Child, Preschool;
Clobetasol;
administration & dosage;
Foreskin;
Gels;
Humans;
Male;
Outpatients;
Phimosis;
drug therapy;
Retrospective Studies;
Treatment Outcome
- From:
National Journal of Andrology
2017;23(7):635-638
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical effect of 0.02% clobetasol propionate cream (CPC) on phimosis in prepubertal children.
METHODS:We retrospectively analyzed the clinical data about 237 prepubertal children with phimosis present at the Outpatient Department from June 2012 to December 2015. The patients were aged 2－14 (mean 8.6) years, all treated by topical application of 0.02% CPC to the narrowed opening and adhered part of the foreskin twice a day, in the morning and evening respectively. At the time of CPC application, the foreskin was slightly retracted. We evaluated the therapeutic effect every week from the end of the first week of treatment.
RESULTS:Totally, 233 of the patients completed the 8-week treatment, of whom 181 (77.68%) showed full retraction of the foreskin, 28 (12.01%) experienced improvement (disappearance of the phimotic ring), and 24 (10.30%) failed to respond, with a total effectiveness rate of 89.70%. No significant local or systemic adverse reactions were observed during the treatment.
CONCLUSIONS:Topical application of 0.02% Clobetasol Propionate Cream is a safe, effective, painless, and inexpensive option for the treatment of phimosis in prepubertal chilodren.
