Orchidopexy increases the levels of serum anti-Müllerian hormone and inhibin B in cryptorchidism patients.
- Author:
Shun-Shun CAO
1
;
Yang-Yang HU
2
;
Cun-Jin NAN
3
Author Information
1. Department of Endocrinology and Inherited Metabolism of Children,The Second Hospital Affiliated to Wenzhou Medical University, Wenzhou, Zhejiang 325000, China.
2. Center of Reproductive Medicine, The Second Hospital Affiliated to Wenzhou Medical University, Wenzhou, Zhejiang 325000, China.
3. Department of Urology, The Second Hospital Affiliated to Wenzhou Medical University, Wenzhou, Zhejiang 325000, China.
- Publication Type:Journal Article
- Keywords:
anti-Müllerian hormone;
inhibin B;
orchidopexy
- MeSH:
Anti-Mullerian Hormone;
blood;
Case-Control Studies;
Cryptorchidism;
blood;
pathology;
surgery;
Humans;
Inhibins;
blood;
Male;
Orchiopexy;
Organ Size;
Penis;
anatomy & histology;
Postoperative Period;
Preoperative Period
- From:
National Journal of Andrology
2017;23(8):713-716
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the levels of serum anti-Müllerian hormone (AMH) and inhibin B (INHB) in patients with unilateral cryptorchidism before and after orchidopexy.
METHODS:This study included 58 cases of unilateral cryptorchidism treated by orchidopexy and 32 healthy controls. Before and at 6 months after surgery, we measured the length and circumference of the penis, the volume of the undescended testis, and levels of serum AMH and INHB.
RESULTS:There were statistically significant differences between the unilateral cryptorchidism and healthy control groups in the levels of serum AMH (［102.80 ± 17.35 vs 108.76 ± 13.64］ ng/ml, P<0.05) and INHB (［70.24 ± 5.73］ vs ［ 77.72 ± 5.94］ pg/ml, P<0.05) at the baseline, but not at 6 months after orchidopexy (AMH: ［109.76 ± 17.25］ vs ［108.03 ± 14.13］ ng/ml, P>0.05; INHB: ［75.76 ± 5.94］ vs ［77.63 ± 5.99］ pg/ml, P>0.05). No remarkable differences were observed between the unilateral cryptorchidism and healthy control groups in the preoperative penile length (［2.05 ± 0.23］ vs ［2.11 ± 0.22］ cm, P>0.05), penile circumference (［3.91 ± 0.23］ vs ［3.99 ± 0.20］ cm, P>0.05) and volume of the undescended testis (［0.45 ± 0.02］ vs ［0.46 ± 0.02］ ml, P>0.05), or in the postoperative penile length (［2.09 ± 0.23］ vs ［2.16 ± 0.22］ cm, P>0.05), penile circumference (［4.00 ± 0.25］ vs ［3.98 ± 0.19］ cm, P>0.05) and volume of the undescended testis (［0.45 ± 0.02］ vs ［0.45 ± 0.02］ ml, P>0.05). Compared with the baseline, the cryptorchidism patients showed markedly increased levels of serum AMH (［102.80 ± 17.35］ vs ［109.76 ± 17.25］ ng/ml, P<0.05) and INHB (［70.24 ± 5.73］ vs ［75.76 ± 5.94］ pg/ml, P<0.05) after orchidopexy.
CONCLUSIONS:Orchidopexy can elevate the levels of serum AMH and INHB and protect the testicular function of cryptorchidism patients.
