Micro-dissection testicular sperm extraction for patients with non-obstructive azoospermia: A report of 196 cases.
- Author:
Jing ZHANG
1
;
Gui-Hua LIU
1
;
Lu-Gang ZHAO
1
;
Xiao-Yan LIANG
1
;
Zhong-Yang WANG
1
Author Information
1. Center of Reproductive Medicine, The Sixth Hospital Affiliated to Sun Yat-sen University, Guangzhou, Guangdong 510620, China.
- Publication Type:Journal Article
- Keywords:
microdissection;
testicular sperm extraction;
azoospermia
- MeSH:
Age Factors;
Azoospermia;
blood;
etiology;
Cryptorchidism;
blood;
complications;
Follicle Stimulating Hormone;
blood;
Humans;
Klinefelter Syndrome;
complications;
Male;
Microdissection;
methods;
Orchitis;
complications;
Retrospective Studies;
Sperm Retrieval;
statistics & numerical data;
Spermatozoa;
Testis;
anatomy & histology
- From:
National Journal of Andrology
2017;23(9):804-807
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of micro-dissection testicular sperm extraction (microTESE) for patients with non-obstructive azoospermia (NOA) and the indications of the strategy.
METHODS:This retrospective study included 196 cases of NOA undergoing microTESE in our center from September 2014 to March 2017. We recorded the sperm retrieval rate (SRR) and analyzed its correlation with the patients' age, testis volume, level of blood follicle-stimulating hormone (FSH), and etiological factors.
RESULTS:Testicular sperm were successfully retrieved from 87 (44.4%) of the patients. No significant correlation was found between the SRR and the patients' age, testis volume, or blood FSH level (P >0.05). As regards etiological factors, the SRR was 100% (29/29) in the patients with orchitis, 66.7% (16/24) in those surgically treated for cryptorchidism, 55.6% (10/18) in those with other secondary testis lesions, 60.0% (3/5) in those with AZFc deletion, 40.9% (9/22) in those with severe idiopathic testicular atrophy, 21.4% (12/56) in those with idiopathic NOA, 20.5% (8/39) in those with Klinefelter's syndrome, and 0% (0/3) in those with other abnormal karyotypes.
CONCLUSIONS:MicroTESE is an effective strategy for sperm retrieval in NOA patients, and the SRR is correlated with etiological factors but not with the FSH level or testis volume of the patients.
