Microdissection testicular sperm extraction for patients with non-mosaic Klinefelter's syndrome: An update.
- Author:
Zhe YU
1
;
Jun YANG
1
;
Ji-Hong LIU
1
Author Information
1. Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China.
- Publication Type:Journal Article
- Keywords:
intracytoplasmic sperm injection;
male infertility;
microdissection testicular sperm extraction;
non-obstructive azoospermia;
pre-implantation diagnosis;
sperm retrieval;
testosterone;
Klinefelter's syndrome
- MeSH:
Adult;
Humans;
Klinefelter Syndrome;
genetics;
Male;
Microdissection;
adverse effects;
methods;
Postoperative Complications;
etiology;
Sperm Retrieval;
Spermatozoa;
Testis;
Testosterone
- From:
National Journal of Andrology
2017;23(9):842-847
- CountryChina
- Language:Chinese
-
Abstract:
Klinefelter's syndrome (KS) is a most frequent sex chromosomal disorder in males, which is characterized by hypogonadism and infertility. The development of assisted reproductive technology has made it possible for KS males to father children. Microdissection testicular sperm extraction (mTESE) is widely considered to be the best method for sperm retrieval in KS patients. This article presents an overview on mTESE for men with non-mosaic KS in the aspects of its predictors, sperm retrieval rate, operation procedure, preoperative hormonal therapy, and postoperative complications and testosterone reduction.
