Thulium laser vaporization versus transurethral resection of the prostate and risk factors for postoperative urethral stricture.
- Author:
Wen SONG
1
;
Tao WANG
1
;
Qing LING
1
;
Xia-Ming LIU
1
;
Zhong CHEN
1
;
Xiao-Dong SONG
1
;
Xiao-Lin GUO
1
;
Qian-Yuan ZHUANG
1
;
Shao-Gang WANG
1
;
Ji-Hong LIU
1
Author Information
1. Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
- Publication Type:Journal Article
- Keywords:
risk factors;
transurethral resection of the prostate;
urethral stricture;
thulium laser vaporization of the prostate
- MeSH:
Humans;
Laser Therapy;
adverse effects;
methods;
Male;
Operative Time;
Postoperative Complications;
etiology;
Prostatic Hyperplasia;
surgery;
Quality of Life;
Regression Analysis;
Risk Factors;
Thulium;
therapeutic use;
Transurethral Resection of Prostate;
adverse effects;
Treatment Outcome;
Urethral Stricture;
etiology;
Urinary Catheterization;
Urinary Tract Infections;
complications
- From:
National Journal of Andrology
2017;23(12):1085-1088
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare thulium laser vaporization of the prostate (TLVP) and transurethral resection of the prostate (TURP) in the treatment of benign prostate hyperplasia (BPH) analyze the risk factors for postoperative urethral stricture.
METHODS:From June 2015 to June 2016, 210 BPH patients in our hospital underwent TURP (n = 126) or TLVP (n = 84). We followed up the patients for 6 months, compared the effects of the two surgical strategies and analyzed the risk factors for postoperative urethral stricture by multivariate logistic regression analysis.
RESULTS:Compared with TURP, TLVP achieved significantly shorter time of operation ([78.6 ± 27.5] vs [53.2 ± 21.6] min, P <0.01), postoperative bladder irrigation ([31.5 ± 2.9] vs [26.1 ± 3.7] h, P <0.01), urethral catheterization ([5.3 ± 1.7] vs [3.7 ± 1.5] d, P <0.01) and postoperative hospitalization ([7.9 ± 2.1] vs [5.5 ± 1.4] d, P <0.01) as well as lower urinary leukocyte count at 6 months after surgery ([32.1 ± 12.6] vs [24.9 ± 11.7] /μl, P <0.01) and incidence rate of postoperative complications (11.9% [15/126] vs 3.6% [3/84], P <0.05), particularly that of urethral stricture (7.9% [10/126] vs 1.2% [1/84], P <0.05). Logistic regression analysis showed that the preoperative urinary leukocyte count, postoperative urethral catheterization time, and surgical method were independent risk factors for postoperative urethral stricture.
CONCLUSIONS:TLVP, in comparison with TURP, has the advantages of definite effect, fast recovery, high safety and low incidence of postoperative urethral stricture. The main risk factors for postoperative urethral stricture include preoperative urinary tract infection, postoperative urethral catheterization time and surgical method.