Surgical treatment of advanced penile cancer without distant metastasis.
- Author:
Xiang WAN
1
;
Ke ZHANG
1
;
Hai-Jun YAO
1
;
Wen-Zhi LI
1
;
Juan ZHOU
1
;
Ming-Xi XU
1
;
Zhong WANG
1
Author Information
1. Department of Urology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China.
- Publication Type:Journal Article
- Keywords:
advanced penile cancer;
nondistant metastasis;
surgery
- MeSH:
Adult;
Aged;
Combined Modality Therapy;
Follow-Up Studies;
Humans;
Lymph Node Excision;
Lymphatic Metastasis;
Male;
Middle Aged;
Penile Neoplasms;
mortality;
pathology;
surgery;
Penis;
surgery;
Prognosis;
Surgical Flaps
- From:
National Journal of Andrology
2017;23(2):147-151
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of surgery on advanced penile cancer without distant metastasis and the factors influencing the prognosis.
METHODS:Between September 2007 and July 2015, we treated 8 cases of advanced penile cancer without distant metastasis by penectomy and lymph node dissection. The patients were aged 37－67 (mean 51.1) years. We followed up the patients for 4－60 (mean 19.25) months postoperatively and analyzed the surgical effects and the factors affecting the prognosis.
RESULTS:Three of the patients remained alive while the other 5 (62.5%) died at 4－13 (mean 9) months after surgery. No significant complications were observed and myocutaneous flap repair showed good prognosis in 4 of the patients with largearea skin defect.
CONCLUSIONS:Surgery is comparatively a valuable option for the treatment of advanced penile cancer without distant metastasis, though with a poor prognosis, and the important factor affecting its prognosis is lymph node metastasis. Flap repair can solve the problem of largearea skin defect after surgery. However, evidence is not yet sufficient to prove the effectiveness of multimodality therapy of this malignancy.
