Correlation of connexin 43 with testicular tumors.
- Author:
Bin-Bin YU
1
;
Ying CAO
1
Author Information
1. Department of Pharmacy, Zhangjiagang First People's Hospital, Zhangjiagang, Jiangsu 215600, China .
- Publication Type:Journal Article
- Keywords:
testicular tumor;
connexin 43;
gap junction
- MeSH:
Animals;
Cell Communication;
Cell Differentiation;
Connexin 43;
metabolism;
Gap Junctions;
metabolism;
Male;
Testicular Neoplasms;
metabolism
- From:
National Journal of Andrology
2017;23(3):267-270
- CountryChina
- Language:Chinese
-
Abstract:
Gap junctions (GJ), as a special membrane structure between adjacent cells, are composed of connexins (Cx) and regulate the proliferation and differentiation of cells. Studies show that gap junctional intercellular communication is weakened or lost in most tumor cells and this abnormality is often accompanied by changed expression of Cxs. Cx43 is a major connexin in the testis tissue. This review focuses on the latest progress in the studies of Cx43 in testicular tumors.
