Transrectal ultrasound conductance-guided administration of traditional Chinese medicine for histological prostatitis in men with small-size BPH and LUTS after TURP.
- Author:
Lei YUAN
1
;
Li-Jiang REN
1
;
Guo-Hui ZHU
1
;
Yong-Chuan WANG
2
;
Xiao-Li ZHANG
1
;
Jing DU
2
;
Ji-Shun SONG
1
Author Information
1. Department of Urology, Shouguang Hospital of Traditional Chinese Medicine, Shouguang, Shandong 262700, China.
2. Department of Urology, Weifang Hospital of Traditional Chinese Medicine, Weifang, Shandong 261041, China.
- Publication Type:Journal Article
- Keywords:
histological prostatitis;
traditional Chinese medicine;
transurethral resection of the prostate;
ultrasound conductance;
benign prostate hyperplasia
- MeSH:
Drugs, Chinese Herbal;
administration & dosage;
Humans;
Lower Urinary Tract Symptoms;
drug therapy;
Male;
Medicine, Chinese Traditional;
methods;
Prostatic Hyperplasia;
drug therapy;
pathology;
Prostatitis;
drug therapy;
pathology;
Quality of Life;
Transurethral Resection of Prostate;
Treatment Outcome;
Ultrasonography, Interventional;
methods
- From:
National Journal of Andrology
2017;23(5):459-463
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effects of transrectal ultrasound conductance (TRUSC)-guided administration of traditional Chinese medicine on histological prostatitis in men with small-size BPH and low urinary tract symptoms (LUTS) after transurethral resection of the prostate (TURP).
METHODS:This study included 167 BPH patients without surgical contraindications. We randomized the patients into an experimental group (n = 84) and a control group (n = 83), with no statistically significant differences between the two groups in age, prostate volume, International Prostate Symptom Score (IPSS), and quality of life (QoL) (P >0.05). The patients of the experimental group received TRUSC-guided administration of traditional Chinese medicine, qd, for 7 days before TURP, while those of the control group underwent TURP only. After treatment, we compared the results of postoperative pathological examination of the prostate tissue, the histological grade of inflammation, IPSS, and QoL scores between the two groups of patients.
RESULTS:In the experimental group, there were 12 cases of non-inflammation (14.3%), 43 cases of mild inflammation (51.2%), 28 cases of moderate inflammation (33.3%), and 1 case of severe inflammation (1.2%), as compared with 8 cases of non-inflammation (9.6%), 28 cases of mild inflammation (33.7%), 45 cases of moderate inflammation (51.8%), and 2 cases of severe inflammation (2.4%) in the control group (P <0.05). Compared with the baseline, both the experimental and control groups showed significant improvement at 4 weeks after surgery in IPSS (22.20±4.14 vs 4.26±2.64 and 23.05±4.11 vs 7.02±4.15, P <0.05) and QoL scores (4.33±0.83 vs 1.25±1.64 and 4.25±0.91 vs 2.05±1.95, P <0.05).
CONCLUSIONS:TRUSC-guided administration of traditional Chinese medicine can significantly alleviate histological inflammation and improve QoL in men with small-size BPH and LUTS after TURP.
