A Case of SAHA Syndrome.
- Author:
Kwang Jun LEE
1
;
Hye Jin CHO
;
Yun Lim CHOI
;
Eil Soo LEE
;
Dong Youn LEE
Author Information
- Publication Type:Case Report
- Keywords: Acne; Alopecia; Hirsutism; SAHA syndrome; Seborrhea
- MeSH: Acne Vulgaris; Adolescent; Alopecia; Androgens; Dermatitis, Seborrheic; Female; Hirsutism; Humans; Hyperandrogenism; Insulin Resistance; Polycystic Ovary Syndrome
- From:Korean Journal of Dermatology 2006;44(6):779-781
- CountryRepublic of Korea
- Language:Korean
- Abstract: The SAHA syndrome is an acronym which stands for seborrhea, acne, hirsutism and androgenic alopecia. The SAHA syndrome generally occurs in young to middle-aged women and may be caused by elevated blood levels of androgens or increased androgen-driven peripheral response with normal circulating androgen levels. In SAHA syndrome, careful diagnostic and clinical evaluation is necessary in order to identify the cause of peripheral hyperandrogenism, and to exclude androgen-producing tumors. SAHA can be classified into 5 subtypes: familial, ovarian, adrenal, hyperprolactinemic SAHA and HAIRAN (hyperandrogenism, insulin resistance, acanthosis nigricans) syndrome. Among them, ovarian SAHA syndrome is associated with polycystic ovarian syndrome. We report a case of ovarian SAHA syndrome in 15-year-old girl who showed seborrea, acne, hirsutism and androgenic alopecia associated with polycystic ovarian syndrome.