A new feruloyl tyramine glycoside from the roots of Achyranthes bidentata.
10.1016/S1875-5364(12)60003-X
- Author:
Liu YANG
1
;
Hai JIANG
;
Qiu-Hong WANG
;
Bing-You YANG
;
Hai-Xue KUANG
Author Information
1. Key Laboratory of Chinese Materia Medica (Heilongjiang University of Chinese Medicine), Ministry of Education, Harbin 150040, China.
- Publication Type:Journal Article
- MeSH:
Achyranthes;
chemistry;
Glucosides;
chemistry;
isolation & purification;
Molecular Structure;
Plant Extracts;
chemistry;
Plant Roots;
chemistry;
Saponins;
chemistry;
isolation & purification;
Triterpenes;
chemistry;
isolation & purification;
Tyramine;
analogs & derivatives;
chemistry;
isolation & purification
- From:
Chinese Journal of Natural Medicines (English Ed.)
2012;10(1):16-19
- CountryChina
- Language:English
-
Abstract:
AIM:To study the chemical constituents of the roots of Achyranthes bidentata Bl.
METHODS:The chemical constituents were isolated and purified by macroporous adsorptive resin D101, silica gel, and ODS column chromatographies and preparetive HPLC. Their structures were elucidated on the basis of 1D and 2D NMR analyses.
RESULTS:Two feruloyl tyramine glycosides and seven triterpenoid saponins were obtained and identified as N-trans-feruloyl-3-methoxytyramine-4'-O-β-D-glucopyranoside (1), N-trans-feruloyl-3-methoxytyra mine-4-O-β-D-glucopyranoside (2), PJS-1 (3), chikusetsusaponin IVa (4), oleanolic acid 3-O-[β-D-glucuronopy ranoside-6-O-methyl ester]-28-O-β-D-glucopyranoside (5), oleanolic acid 3-O-[β-D-glucuronopyran-oside-6-O-ethylester]-28-O-β-D-glucopyranoside (6), oleanolic acid 3-O-[β-D-glucuronopyranoside-6-O-butyl ester]-28-O-β-D-glucopyranoside (7), ginsenoside R(0) (8) and hederagenin-28-O-β-D-glucopyranosyl ester (9).
CONCLUSION:Compound 1 is a new feruloyl tyramine glycoside, while compounds 2 and 9 are reported from A. bidentata for the first time.
