Chemical constituents of Cinnamomum cebuense.
10.1016/S1875-5364(13)60026-6
- Author:
Consolacion Y RAGASA
1
;
Dinah L ESPINELI
;
Esperanza Maribel G AGOO
;
Ramon S DEL FIERRO
Author Information
1. Chemistry Department and Center for Natural Sciences and Ecological Research, De La Salle University, Manila, Philippines. consolacion.ragasa@dlsu.edu.ph
- Publication Type:Journal Article
- MeSH:
Cinnamomum;
chemistry;
Magnetic Resonance Spectroscopy;
Philippines;
Plant Bark;
chemistry;
Plant Extracts;
chemistry;
isolation & purification;
Plant Leaves;
chemistry;
Triterpenes;
chemistry;
isolation & purification
- From:
Chinese Journal of Natural Medicines (English Ed.)
2013;11(3):264-268
- CountryChina
- Language:English
-
Abstract:
AIM:To investigate the chemical constituents of Cinnamomum cebuense, an endemic and critically endangered tree found only in Cebu, Philippines.
METHODS:The compounds were isolated by silica gel chromatography. The structures of the isolates were elucidated by NMR spectroscopy.
RESULTS:The dichloromethane (DCM) extract of the bark of C. cebuense afforded a new monoterpene natural product 1 and a new sesquiterpene 2, along with the known compounds, 4-hydroxy-3-methoxycinnamaldehyde (3), 4-allyl-2-methoxyphenol (4), α-terpineol (5) and humulene (6). The DCM extract of the leaves of C. cebuense yielded 6, β-caryophyllene (7), squalene (8), and a mixture of α-amyrin (9), β-amyrin (10) and bauerenol (11). The structures of 1-7 were elucidated by extensive 1D and 2D NMR spectroscopy, while the structures of 8-11 were identified by comparison of their (13)C NMR data with those reported in the literature.
CONCLUSION:The bark of C. cebuense afforded monoterpenes, sesquiterpenes and phenolics, while the leaves yielded sesquiterpenes and triterpenes.