A Case of Etoposide Therapy in a Patient Newly Diagnosed with Classic Kaposi's Sarcoma and Rheumatoid Arthritis.
- Author:
Nan Young CHOI
1
;
Seung Ah PARK
;
Bo Ram HAN
;
Ho Young KIM
;
Soo Kee MIN
;
Hyo Jung KIM
;
Dae Young ZANG
Author Information
1. Department of Internal Medicine, Hallym University College of Medicine, Anyang, Korea. hemonc@hallym.or.kr
- Publication Type:Case Report
- Keywords:
HIV;
Sarcoma, Kaposi;
Herpesvirus 8, Human;
Etoposide;
Arthritis, Rheumatoid
- MeSH:
Acquired Immunodeficiency Syndrome;
Aged;
Arthritis, Rheumatoid*;
Biopsy;
Etoposide*;
Herpesvirus 8, Human;
HIV;
HIV Antibodies;
Humans;
Immunocompromised Host;
Male;
Sarcoma, Kaposi*;
Skin
- From:Korean Journal of Medicine
2014;86(2):247-252
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Kaposi's sarcoma typically occurs in immunocompromised patients, especially those with acquired immunodeficiency syndrome. Human herpesvirus 8 (HHV-8) and human immunodeficiency virus (HIV) may play important roles in the development of Kaposi's sarcoma. We report the case of a 75-year-old male who presented with progressive multiple purplish papules and nodules on the skin for 3 months. Social and past medical histories seemed incompatible with an immunesuppressed condition and tests for HIV antibodies and HHV-8 were negative. He was newly diagnosed with rheumatoid arthritis, according to the 2010 ACR-EULAR criteria. Typical findings of Kaposi's sarcoma were confirmed by biopsy. After treatment with metronomic oral etoposide 25 mg once daily for 9 months, the skin lesions had almost resolved with no serious complication. Thus, we report a rare case of Kaposi's sarcoma developing in a patient with newly diagnosed rheumatoid arthritis who showed a good response to oral etoposide.
