A new diterpenoid alkaloid isolated from Delphinium caeruleum.
10.1016/S1875-5364(17)30007-9
- Author:
Chao-Zhan LIN
1
;
Zhu-Jie LIU
1
;
Zeren-Dawa BAIRI
2
;
Chen-Chen ZHU
3
Author Information
1. Institute of Clinical Pharmacology, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
2. Tibetan Traditional Medical College, Lasa 850000, China.
3. Institute of Clinical Pharmacology, Guangzhou University of Chinese Medicine, Guangzhou 510405, China. Electronic address: zhuchenchen@vip.sina.com.
- Publication Type:Journal Article
- Keywords:
Alkaloids;
Caerudelphinine A;
Delphinium caeruleum
- MeSH:
Aconitine;
analogs & derivatives;
chemistry;
isolation & purification;
Alkaloids;
chemistry;
isolation & purification;
Aporphines;
chemistry;
isolation & purification;
Delphinium;
chemistry;
Diterpenes;
chemistry;
isolation & purification;
Magnetic Resonance Spectroscopy;
Molecular Structure;
Plant Components, Aerial;
chemistry;
Plant Extracts;
chemistry
- From:
Chinese Journal of Natural Medicines (English Ed.)
2017;15(1):45-48
- CountryChina
- Language:English
-
Abstract:
The present study was designed to determine the chemical constituents of Delphinium caeruleum Jacq. ex Camb.. The chemical constituents were isolated and purified by column chromatography with silica gel, ODS, and Sephadex LH-20. Their structures were elucidated by IR, MS, and NMR. Ten compounds were obtained and identified as caerudelphinine A (1), lycoctonine (2), talitine B (3), talitine A (4), talitine C (5), tatsienine-V (6), d-magnoflorine (7), 2-trimethyl-ammonio-3-(3-indolyl) propionate (8), vakhmatine (9), and delatisine (10). Compound 1 was a new lycoctonine-type C19-diterpenoid alkaloid, and compounds 4-10 were isolated from this plant for the first time.
