Non-alkaloid constituents of Vinca major.
10.3724/SP.J.1009.2016.00056
- Author:
Gui-Guang CHENG
1
,
2
;
Hai-Yun ZHAO
3
;
Lu LIU
4
;
Yun-Li ZHAO
4
;
Chang-Wei SONG
4
;
Ji GU
4
;
Wei-Bang SUN
4
;
Ya-Ping LIU
5
;
Xiao-Dong LUO
6
Author Information
1. Yunnan Institute of Food Safety, Kunming University of Science and Technology, Kunming, 650500, China
2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.
3. Yunnan Institute of Food Safety, Kunming University of Science and Technology, Kunming, 650500, China.
4. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.
5. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China. Electronic address: liuyaping@mail.kib.ac.cn.
6. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China. Electronic address: xdluo@mail.kib.ac.cn.
- Publication Type:Journal Article
- Keywords:
Antioxidant;
Iridoid glycoside;
Vinca major;
Vinmaside A
- MeSH:
Antioxidants;
pharmacology;
Iridoid Glycosides;
chemistry;
isolation & purification;
pharmacology;
Plant Leaves;
chemistry;
Plant Stems;
chemistry;
Vinca;
chemistry
- From:
Chinese Journal of Natural Medicines (English Ed.)
2016;14(1):56-60
- CountryChina
- Language:English
-
Abstract:
The present study was designed to investigate the non-alkaloid compounds from the leaves and stems of Vinca major cultivated in Yunnan Province, China. The compounds were isolated using chromatographic techniques. The structures were elucidated by 1D- and 2D-NMR spectroscopic methods in combination with UV, IR, and MS analyses. The 1, 1-diphenyl-2-picrylhydrazyl (DPPH)-scavenging activity of Compounds 1-7 were evaluated. One new iridoid glycoside (compound 1), together with 11 known compounds, were isolated from Vinca major. Compounds 1, 5, and 6 showed moderate DPPH-scavenging activity, with IC50 values being 70.6, 32.8, and 62.2 μmol·L(-1), respectively. In conclusion, compound 1 is a newly identified iridoid glycoside with moderate antioxidant activity.
