Antimicrobial metabolites from marine microorganisms.
10.1016/S1875-5364(16)60003-1
- Author:
Prasanna HABBU
1
;
Vijayanand WARAD
2
;
Rajesh SHASTRI
3
;
Smita MADAGUNDI
3
;
Venkatrao H KULKARNI
4
Author Information
1. Postgraduate Department of Pharmacognosy & Phytochemistry, SET's College of Pharmacy, Dharwad 580002, Karnataka, India. Electronic address: prasherbs@yahoo.com.
2. Department of Pharmacognosy and Phytochemistry, Sridevi College of Pharmacy, Mangalore 575006, Karnataka, India.
3. Postgraduate Department of Pharmacognosy & Phytochemistry, SET's College of Pharmacy, Dharwad 580002, Karnataka, India.
4. Postgraduate Department of Pharmacology, SET's College of Pharmacy, Dharwad 580002, Karnataka, India.
- Publication Type:Journal Article
- Keywords:
Antibacterial metabolites;
Antifungal metabolites;
Marine microbes
- MeSH:
Anti-Infective Agents;
chemistry;
metabolism;
pharmacology;
Bacteria;
chemistry;
isolation & purification;
metabolism;
Fungi;
chemistry;
isolation & purification;
metabolism;
Seawater;
microbiology
- From:
Chinese Journal of Natural Medicines (English Ed.)
2016;14(2):101-116
- CountryChina
- Language:English
-
Abstract:
Marine ecological niches have recently been described as "particularly promising" sources for search of new antimicrobials to combat antibiotic-resistant strains of pathogenic microorganisms. Marine organisms are excellent sources for many industrial products, but they are partly explored. Over 30 000 compounds have been isolated from marine sources. Bacteria, fungi, and cyanobacteria obtained from various marine sources secret several industrially useful bioactive compounds, possessing antibacterial, antifungal, and antimycobacterial activities. Sustainable cultivation methods for promising marine organisms and biotechnological processes for selected compounds can be developed, along with the establishment of biosensors for monitoring the target compounds. The semisynthetic modifications of marine-based bioactive compounds produce their new derivatives, structural analogs and mimetics that could serve as novel lead compounds against resistant pathogens. The present review focuses on promising antimicrobial compounds isolated from marine microbes from 1991-2013.
