Lobelia chinensis: chemical constituents and anticancer activity perspective.
10.1016/S1875-5364(14)60016-9
- Author:
Mei-Wan CHEN
1
;
Wen-Rong CHEN
2
;
Jin-Ming ZHANG
1
;
Xiao-Ying LONG
2
;
Yi-Tao WANG
3
Author Information
1. State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau 999078, China.
2. School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China.
3. State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau 999078, China. Electronic address: ytwang@umac.mo.
- Publication Type:Journal Article
- Keywords:
Anticancer activity;
Chemical constituents;
Lobelia chinensis
- MeSH:
Alkaloids;
pharmacology;
therapeutic use;
Animals;
Antineoplastic Agents, Phytogenic;
pharmacology;
therapeutic use;
Flavonoids;
pharmacology;
therapeutic use;
Humans;
Lobelia;
chemistry;
Neoplasms;
drug therapy;
Phytotherapy;
Plant Extracts;
pharmacology;
therapeutic use
- From:
Chinese Journal of Natural Medicines (English Ed.)
2014;12(2):103-107
- CountryChina
- Language:English
-
Abstract:
Research has demonstrated that many chemical constituents dominated by piperidine alkaloids and flavonoids, such as lobelanidine, lobeline, and lobelanine, have been obtained from Lobelia chinensis Lour. Experimental studies and clinical applications have also indicated that L. chinensis possesses a number of pharmacological activities (e.g., diuretic, choleretic, breathing excitement, anti-venom, anti-bacterial, and anticancer). This paper focuses on the properties, chemical constituents, and anticancer activity of L. chinensis to clarify the connection among them, and identify the active anticancer compounds. This work serves as the foundation for further research and development of L. chinensis.
