Two new steroidal saponins from the rhizomes of Dioscorea zingiberensis.
10.1016/S1875-5364(14)60023-6
- Author:
Lu ZHENG
1
;
Yuan ZHOU
1
;
Jia-Yu ZHANG
2
;
Min SONG
1
;
Ye YUAN
1
;
Yan-Jiao XIAO
1
;
Ting XIANG
3
Author Information
1. Research Institute of Traditional Chinese Medicine, Yangtze River Pharmaceutical Group Co., Ltd., Taizhou, 225321, China.
2. School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100029, China.
3. Research Institute of Traditional Chinese Medicine, Yangtze River Pharmaceutical Group Co., Ltd., Taizhou, 225321, China. Electronic address: tingxiang39@163.com.
- Publication Type:Journal Article
- Keywords:
Dioscorea zingiberensis;
Dioscoreaceae;
Steroidal saponins;
Zingiberenoside
- MeSH:
Dioscorea;
chemistry;
Diosgenin;
chemistry;
isolation & purification;
Molecular Structure;
Plant Extracts;
chemistry;
Rhizome;
chemistry;
Saponins;
chemistry;
isolation & purification;
Spirostans;
chemistry;
isolation & purification;
Steroids;
chemistry;
isolation & purification
- From:
Chinese Journal of Natural Medicines (English Ed.)
2014;12(2):142-147
- CountryChina
- Language:English
-
Abstract:
AIM:To investigate the chemical constituents of Dioscorea zingiberensis C. H. Wright.
METHODS:The compounds were isolated by various chromatographic techniques, and the structures of the new steroidal saponins were elucidated by extensive 1D- and 2D-NMR, MS, and IR spectral analysis.
RESULTS:The 70% EtOH extract of the rhizomes of Dioscorea zingiberensis afforded two new steroidal saponins, zingiberenosides A (1) and B (2), along with eight known analogues, 3β, 26-dihydroxy-25(R)-furosta-Δ(5, 20(22))-diene-3-O-α-L- rhamnopyranosyl-(1→2)-O-β-D-glucopyranoside (3), methyl parvifloside (4), deltoside (5), methyl deltoside (6), zingiberensis new saponin (7), deltonin (8), progenin III (9) and diosgenin-diglucoside (10).
CONCLUSION:Two new steroidal saponins were isolated from Dioscorea zingiberensis and their structures determined.
