Metabolites from the endophytic fungus HP-1 of Chinese eaglewood.
10.1016/S1875-5364(14)60025-X
- Author:
Wen-Jian ZUO
1
;
Peng-Fei JIN
1
;
Wen-Hua DONG
1
;
Hao-Fu DAI
1
;
Wen-Li MEI
2
Author Information
1. Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.
2. Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China. Electronic address: meiwenli@itbb.org.cn.
- Publication Type:Journal Article
- Keywords:
Antibacterial activity;
Chaetomium sp.;
Chinese eaglewood;
Endophytic fungus;
Metabolites
- MeSH:
Anti-Bacterial Agents;
chemistry;
isolation & purification;
pharmacology;
Endophytes;
chemistry;
Fungi;
chemistry;
Phenylacetates;
chemistry;
isolation & purification;
pharmacology;
Sesquiterpenes;
chemistry;
isolation & purification;
Thymelaeaceae;
microbiology;
Wood;
microbiology
- From:
Chinese Journal of Natural Medicines (English Ed.)
2014;12(2):151-153
- CountryChina
- Language:English
-
Abstract:
AIM:To study the chemical constituents from the fermentation of the endophytic fungus HP-1 of Chinese eaglewood.
METHODS:The chemical constituents were isolated by column chromatography on silica gel and Sephadex LH-20, and their structures were elucidated on the basis of spectroscopic analysis.
RESULTS:Four compounds were isolated and identified as 3α, 3β, 10β-trimethyl-decahydroazuleno[6, 7]furan-8, 9, 14-triol (1), 4-hydroxyphenylacetic acid (2), 4-hydroxyphenethyl alcohol (3), and 5-hydroxymethyl-2-furancarboxaldehyde (4).
CONCLUSION:Compound 1 was a new compound. Compound 2 showed antibacterial activity against Staphylococcus aureus.
