Cardioprotective and antioxidant effects of oleogum resin "Olibanum" from Bos Boswellia carteri Birdw. (Bursearceae).
10.1016/S1875-5364(14)60042-X
- Author:
Ahmed A ZAKI
1
;
Nadia E HASHISH
2
;
Mohamed A AMER
2
;
Mohamed-Farid LAHLOUB
2
Author Information
1. Pharmacognosy Department, Faculty of Pharmacy, Mansoura University, 35516, Egypt. Electronic address: ahmedawadzaki@yahoo.co.uk.
2. Pharmacognosy Department, Faculty of Pharmacy, Mansoura University, 35516, Egypt.
- Publication Type:Journal Article
- Keywords:
Antioxidant;
Boswellia carteri;
Cardiovascular diseases;
Frankincense;
Olibanum
- MeSH:
Animals;
Antioxidants;
administration & dosage;
analysis;
Boswellia;
chemistry;
Frankincense;
administration & dosage;
analysis;
Humans;
Male;
Myocardial Infarction;
drug therapy;
pathology;
Myocardium;
pathology;
Rats;
Rats, Wistar
- From:
Chinese Journal of Natural Medicines (English Ed.)
2014;12(5):345-350
- CountryChina
- Language:English
-
Abstract:
One of the leading causes of death worldwide is cardiovascular disease, hence searching for a cure is an important endeavor. The totally safe, edible, and inexpensive Boswellia plant exudate, known as olibanum or frankincense, is considered to possess diverse medicinal values in traditional medicine and from recent biological studies. Investigating the cardioprotective and antioxidant activities of olibanum from a Boswellia species, family Bursearaceae, namely Boswellia carteri Birdw. was the aim of this study. Cardioprotective activity was evaluated using a model of myocardial infarction induced by isoprenaline (ISO), while antioxidant activity was tested adopting nitric oxide scavenging (NOS) and azino-bis-3-ethyl benzthiazoline-6-sulfonic acid (ABTS) assays. The results revealed a mild cardioprotective effect and weak antioxidant activity.
