New 9, 19-cycloartane triterpenoid from the root of Cimicifuga foetida.
10.1016/S1875-5364(14)60057-1
- Author:
Di-Fan ZHU
1
,
2
,
3
;
Yin NIAN
3
,
4
;
Hai-Yan WANG
3
,
4
;
Zhi-Run ZHANG
3
,
4
;
Yan-Bo SONG
3
,
4
;
Rong-Tao LI
5
;
Ming-Hua QIU
4
,
6
Author Information
1. Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan 650050, China
2. State Key Laboratory of Phytochemistry and Plant Resources in West China
3. Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.
4. State Key Laboratory of Phytochemistry and Plant Resources in West China
5. Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan 650050, China.
6. Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China. Electronic address: mhchiu@mail.kib.ac.cn.
- Publication Type:Journal Article
- Keywords:
9, 19-Cycloartane triterpene;
Acetoxy groups;
Cimifuga foetida;
Ranuncluaceae
- MeSH:
Cimicifuga;
chemistry;
Drugs, Chinese Herbal;
chemistry;
isolation & purification;
Molecular Structure;
Plant Roots;
chemistry;
Triterpenes;
chemistry;
isolation & purification
- From:
Chinese Journal of Natural Medicines (English Ed.)
2014;12(4):294-296
- CountryChina
- Language:English
-
Abstract:
AIM:To study the 9, 19-cycloartane triterpenes from the roots of Cimicifuga foetida.
METHOD:Chromatographic separations by silica gel, C18 reversed phase silica gel, and high-performance liquid chromatography (HPLC) were used. All of the structures were elucidated on the basis of spectroscopic analysis and chemical methods.
RESULTS:Five 9, 19-cycloartane triterpenes, (3β, 12β, 15α, 24R)-12, 2'-diacetoxy-24, 25-epoxy-15-hydroxy-16, 23-dione-3-O-α-L-arabinopyranoside (1), actein (2), 23-epi-26-deoxyactein (3), asiaticoside B (4), and 12β-hydroxycimigenol (5) were isolated from the roots of Cimicifuga foetida.
CONCLUSION:Compound 1 is a new triterpene with two acetoxy groups at C-2' and C-12.
