Heteroclitins R-S: new dibenzocylooctadiene lignans from Kadsura heteroclita.
10.1016/S1875-5364(14)60105-9
- Author:
Min CHEN
1
;
You-Ping LUO
2
,
3
;
Yan-Lin ZOU
4
;
Ling-Hu LANG
4
;
Dao-Feng CHEN
5
Author Information
1. Key Laboratory on Luminescence and Real-Time Analysis (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China. Electronic address: mminchen@swu.edu.cn.
2. Key Laboratory on Luminescence and Real-Time Analysis (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China
3. College of Chemistry and Chemical Engineering, HaiNan Normal University, Hai Kou 571158, China.
4. Key Laboratory on Luminescence and Real-Time Analysis (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China.
5. Department of Pharmacognosy, School of Pharmacy, Fudan University, Shanghai 201203, China.
- Publication Type:Journal Article
- Keywords:
Dibenzocylooctadiene Lignan;
Heteroclitins R-S;
Kadsura heteroclita;
Schisandraceae
- MeSH:
Kadsura;
chemistry;
Lignans;
chemistry;
isolation & purification;
Molecular Structure;
Plant Extracts;
chemistry
- From:
Chinese Journal of Natural Medicines (English Ed.)
2014;12(9):689-692
- CountryChina
- Language:English
-
Abstract:
AIM:To study the dibenzocylooctadiene lignans from the stems of Kadsura heteroclita.
METHOD:Chromatographic separations of silica gel and semi-preparative HPLC were used. All of the structures were elucidated on the basis of spectroscopic analysis, including 2D-NMR and HR-MS techniques.
RESULTS:Four dibenzocylooctadiene lignans were isolated from K. heteroclita. Their structures were identified as heteroclitin R (1), heteroclitin S (2), gonisin O (3), and schisanlignone A (4).
CONCLUSION:Heteroclitin R (1) and heteroclitin S (2) are new natural lignans.
