A new lignan glycoside from Forsythia suspensa.
10.1016/S1875-5364(14)60107-2
- Author:
Chang LI
1
;
Yi DAI
2
,
3
;
Ying-Hui DUAN
2
,
3
;
Ming-Li LIU
2
,
3
;
Xin-Sheng YAO
4
,
5
,
6
Author Information
1. College of Traditional Mongolian Medicine, Inner Mongolia University for Nationalities, Tongliao 028000, China.
2. Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China
3. Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou 510632, China.
4. College of Traditional Mongolian Medicine, Inner Mongolia University for Nationalities, Tongliao 028000, China
5. Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China
6. Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou 510632, China. Electronic address: tyaoxs@jnu.edu.cn.
- Publication Type:Journal Article
- Keywords:
Chemical constituents;
Forsythia suspensa;
Lignan glycosides
- MeSH:
Forsythia;
chemistry;
Glycosides;
chemistry;
isolation & purification;
Lignans;
chemistry;
isolation & purification;
Molecular Structure;
Plant Extracts;
chemistry
- From:
Chinese Journal of Natural Medicines (English Ed.)
2014;12(9):697-699
- CountryChina
- Language:English
-
Abstract:
Phytochemical investigation on Forsythia suspensa (Thunb.) Vahl afforded ten compounds, including five lignan glycosides and five phenylethanoid glycosides. The compounds were isolated by using HP-20 macroporous resin, silica gel, octadecyl silica gel (ODS), size exclusion chromatography resin HW-40 chromatography, and preparative HPLC. The structures were established through application of extensive spectroscopic methods, including ESI-MS, 1D-and 2D-NMR spectroscopy. They were identified as forsythialanside E (1), 8'-hydroxypinoresinol-4'-O-β-D-glucoside (2), 8'-hydroxypinoresinol (3), lariciresinol-4'-O-β-D-glucoside (4), lariciresinol-4-O-β-D-glucoside (5), forsythoside H (6), forsythoside I (7), forsythoside F (8), plantainoside B (9), and plantainoside A (10). Compound 1 was a new lignan glycoside.
