Two new steroidal saponins isolated from Anemarrhena asphodeloides.
10.1016/S1875-5364(17)30038-9
- Author:
Xing-Huan SUN
1
;
Fu-Tao ZHU
1
;
Yu-Wei ZHANG
1
;
Fang-Fang CHEN
1
;
Yun YU
1
;
Ning-Ning SONG
1
;
Xue-Feng HUANG
2
Author Information
1. State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China.
2. State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China. Electronic address: hxf@cpu.edu.cn.
- Publication Type:Journal Article
- Keywords:
Absolute configuration;
Anemarrhena asphodeloides;
ECD;
Steroidal saponin;
Timosaponin P;
Timosaponin Q
- MeSH:
Anemarrhena;
chemistry;
Drugs, Chinese Herbal;
chemistry;
isolation & purification;
Magnetic Resonance Spectroscopy;
Mass Spectrometry;
Molecular Structure;
Saponins;
chemistry;
isolation & purification;
Steroids;
chemistry;
isolation & purification
- From:
Chinese Journal of Natural Medicines (English Ed.)
2017;15(3):220-224
- CountryChina
- Language:English
-
Abstract:
Two new steroidal saponins, named timosaponin P (1) and timosaponin Q (2), were isolated from the rhizome parts of Anemarrhena asphodeloides Bunge using various chromatographic methods. Their structures and absolute configurations were elucidated by a combination of spectroscopic and spectrometric data, including 1D, 2D NMR, HR-ESI-MS and ECD calculations, and this is the first time the absolute configuration of C-23 of steroidal saponin was confirmed by ECD calculations.
