Case of a Cystic Hypersecretory Duct Carcinoma of the Breast.
- Author:
Sang Chul LEE
1
;
Kee Hwan KIM
;
Chang Hyeok AHN
;
Woo Chan PARK
;
Se Jung OH
;
Jeong Soo KIM
;
Hae Myung JEON
;
Seung Jin YOO
;
Sang Seul JUNG
;
Keun Woo LIM
Author Information
1. Department of Surgery, Uijongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Uijongbu, Korea. drbreast@cmc.cuk.ac.kr
- Publication Type:Case Report
- Keywords:
Breast cancer;
Hypersecretory;
Cystic
- MeSH:
Adenocarcinoma, Follicular;
Adenocarcinoma, Mucinous;
Alcian Blue;
Breast Cyst;
Breast Neoplasms;
Breast*;
Carcinoma, Intraductal, Noninfiltrating;
Diagnosis, Differential;
Dilatation;
Eosinophils;
Epithelium;
Hyperplasia;
Lactalbumin;
Neoplasm Metastasis;
Papilloma;
Thyroid Gland
- From:Journal of the Korean Surgical Society
2002;63(3):247-251
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Breast cystic hypersecretory duct carcinomas (CHDC), characterized by cystic dilatation of ducts, cysts filled with thyroid colloid-like eosinophilic material, and by micropapillary carcinomas in the epithelium lining the cyst, is a rare histological variant of intraductal carcinomas. CHDC is differentiated from cystic hypersecretory hyperplasia. It's clinical manifestations are similar to those of other intraductal carcinomas. CHDC has a low-grade behavior for many years, but can be invasive, with the potential for metastasis. The importance of CHDC is its differentiation from a variety of other lesions of the breast, both benign and malignant. Various differential diagnoses for CHDC include: fibrocystic changes of the breast with microcyst formation, juvenile papillomatosis, benign mucocele-like lesions, juvenile secretory carcinomas, mucin-producing colloid carcinomas and metastatic follicular thyroid carcinomas. Histochemical staining (PAS, alcian blue and mucicarmine) or immunoperoxidase studies (CEA, alpha-lactalbumin and thyroglobulin) may also helpful in differential diagnoses. We report a case of a cystic hypersecretory duct carcinoma (CHDC) of the breast, and present a review of the literature.
