Advances in the role of steroids in rheumatoid arthritis

VernacularTitle:类固醇激素在类风湿性关节炎中的作用研究进展
Author: Chen WANG ¹ ; Xin HUANG ; Zhenzhou Xin ; Luyong ZHANG
Author Information

1. 中国药科大学江苏省新药筛选重点实验室，中国药科大学江苏省药效研究与评价服务中心
Publication Type:Journal Article
Keywords: steroid; rheumatoid arthritis; mechanism; relevance
From: Journal of China Pharmaceutical University 2015;46(6):757-763
CountryChina
Language:Chinese
Abstract: Steroids have been used to treat rheumatoid arthritis(RA), especially glucocorticoids and sex hormones, exhibit powerful and rapid therapeutic effects. The relationship between the steroids and inflammatory cytokine, immune response, nuclear receptors, as well as the safety and efficacy of RA treatment, were introduced in this review. Meanwhile, the possible mechanism of glucocorticoids and sex hormones therapy were discussed. The potential relevance of steroids to RA was also discussed to better use steroids in the treatment of RA and to provide references for future research.