Non-C21 steroids from the Rhizome of Cynanchum stauntonii

VernacularTitle:柳叶白前中非C21甾体类化学成分
Author: Shule YU ^{1
,

2} ; Lin MA ; Zhengfeng WU ; Shouxun ZHAO ; Lei WANG ; Wencai YE ; Jian ZHANG ; Zhiqi YIN
Author Information

1. 中国药科大学天然药物化学教研室&
2. 天然药物活性组分与药效国家重点实验；江苏省中医药研究院转化医学实验室
Publication Type:Journal Article
Keywords: Cynanchum stauntonii; non-C21steroids; chemical constituents; structural identification
From: Journal of China Pharmaceutical University 2015;46(4):426-430
CountryChina
Language:Chinese
Abstract: Twelve compounds were isolated and purified from ethyl acetatefraction of Cynanchum stauntonii by silica gel, Sephadex LH-20 and ODS column chromatography. Their structures were identified by spectral techniques and physicochemical properties as syringaresinol(1), (-)-(7R, 7′R, 7″R, 8S, 8′S, 8″S)-4′, 4″-dihydroxy-3, 3′, 3″, 5-tetramethoxy-7, 9′ ∶7′, 9-diepoxy-4, 8″-oxy-8, 8′-sesquineolignan-7″, 9″-diol(2), prinsepiol(3), 4-hydroxyacetophenone(4), baishouwubenzophenone(5), 2, 4-dihydroxyacetophenone(6), benzoic acid(7), 1, 4-benzenediol(8), 6-O-［E］-sinapoyl-α-D-glucopyranoside(9a), 6-O-［E］-sinapoyl-β-D-glucopyranoside(9b), 1-O-methyl-α-D-cymadropyranoside(10), β-daucosterol(11), and β-sitosterol(12). Compounds 1-3, 5 and 7-11 were firstly isolated from this plant.