Application and research progress of pharmaco-metabonomics in the diagnosis and treatment of tumor
10.11665/j.issn.1000-5048.20150403
- VernacularTitle:药物代谢组学在肿瘤诊治中的应用与研究进展
- Author:
Liujing WEN
1
;
Chen WANG
Author Information
1. 天津医科大学肿瘤医院,天津市肿瘤防治重点实验室
- Publication Type:Journal Article
- Keywords:
metabonomics;
pharmaco-metabonomics;
tumor;
drug resistance;
toxicity;
indivisualized medication
- From:
Journal of China Pharmaceutical University
2015;46(4):400-405
- CountryChina
- Language:Chinese
-
Abstract:
With the development of metabonomics and modern instrumental analysis and bioinformatics, pharmaco-metabonomics has been rapidly put into the diagnosis and treatment of tumor, with a particularly important role in the evaluation and prediction of efficacy, toxicity and resistance of anti-tumor drugs, indivisualized medication and detection of tumor markers. This paper reviews the concept and methodologies of pharmaco-metabonomics, as well as the latest research advances of pharmaco-metabonomics in the diagnosis and freatment of tumors.