Self-assembled peptide:insights and biomedicine applications
10.11665/j.issn.1000-5048.20150219
- VernacularTitle:自组装多肽在生物医药领域的研究进展
- Author:
Chenyu ZHANG
1
;
Xue LI
;
Hai QIAN
;
Wenlong HUANG
Author Information
1. 中国药科大学新药研究中心
- Publication Type:Journal Article
- Keywords:
self-assembled peptides;
drug carrie;
r targeting;
applications
- From:
Journal of China Pharmaceutical University
2015;46(2):250-256
- CountryChina
- Language:Chinese
-
Abstract:
Self-assembled peptides occur via inter-molecular non-covalent assembly, spontaneity or triggering, and the formed nanostructures have been found to have certain features and functions which are not shown by the original peptide molecules or low-hierarchical molecules. There are growing attentions on the self-assembled peptide. This review provides detailed classifications of self-assembled peptides, i. e. , spontaneity and triggering, according to how the self-assemble responds or adjusts to outer environment. In addition, the summary offers potentials of their applications in biomedicine, such as anti-tumor and anti-bacterial medicine, drug carriers modifying pharmaceutical features of drugs, enhanced drug targeting, matrix as cell culture, tissue regeneration, and biomedicinal detection.
