Three-Dimensional Dosimetry Using Magnetic Resonance Imaging of Polymer Gel.
- Author:
Young Taek OH
1
;
Haejin KANG
;
Miwha KIM
;
Mison CHUN
;
Seung Hee KANG
;
Chang Ok SUH
;
Seong Sil CHU
;
Jinsil SEONG
;
Gwi Eon KIM
Author Information
1. Department of Radiation Oncology, Ajou University Shcool of Medicine, Suwon, Korea, ohyoung@madang.ajou.ac.kr
- Publication Type:Original Article
- Keywords:
Conformal radiotherapy;
MRI;
Dosimetry;
Radiation dose;
Polymer gel
- MeSH:
Glass;
Head;
Humans;
Magnetic Resonance Imaging*;
Polymerization;
Polymers*;
Radiometry;
Radiotherapy, Conformal
- From:The Journal of the Korean Society for Therapeutic Radiology and Oncology
2002;20(3):264-273
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Three-dimensional radiation dosimetry using magnetic resonance imaging of polymer gel was recently introduced. This dosimetry system is based on radiation induced chain polymerization of acrylic monomers in a muscle equivalent gel and provide accurate 3 dimensional dose distribution. We planned this study to evaluate the clinical value of this 3-dimensional dosimetry. MATERIALS AND METHODS: The polymer gel poured into a cylindrical glass flask and a spherical glass flask. The cylindrical test tubes were for dose response evaluation and the spherical flasks, which is comparable to the human head, were for isodose curves. T2 maps from MR images were calculated using software, IDL. Dose distributions have been displayed for dosimetry. The same spherical flask of gel and the same irradiation technique was used for film and TLD dosimetry and compared with each other. RESULTS: The R2 of the gel respond linearly with radiation doses in the range of 2 to 15 Gy. The repeated dosimetry of spherical gel showed the same isodose curves. These isodose curves were identical to dose distributions from treatment planning system especially high dose range. In addition, the gel dosimetry system showed comparable or superior results with the film and TLD dosimetry. CONCLUSION: The 3-dimensional dosimetry for conformal radiation therapy using MRI of polymer gel showed stable and accurate results. Although more studies are needed for convenient clinical application, it appears to be a useful tool for conformal radiation therapy.
