A new flavonoid glycoside from the stem barks of Premna fulva
10.11665/j.issn.1000-5048.20160608
- VernacularTitle:战骨中一个新的黄酮苷类成分
- Author:
Xueli WU
1
;
Chulu QI
;
Hao WANG
;
Wencai YE
Author Information
1. 中国药科大学天然药物化学教研室
- Publication Type:Journal Article
- Keywords:
Premna fulva;
verbenaceae;
chemical constituents;
flavonoid;
structural identification;
nitric oxideinhibition
- From:
Journal of China Pharmaceutical University
2016;47(6):678-682
- CountryChina
- Language:Chinese
-
Abstract:
A new flavonoid glycoside, named(2R)-naringenin-5-O-β-D- xylopyranosyl(1→6)-β-D-glucopyranoside(1), together with other eight known compounds(2-9), was isolated and characterized. Compounds 3-5, 7-9 were isolated from the stem barks of Premna fulva for the first time. The anti-inflammatory activities of all the isolates were evaluated for their inhibitory effects against LPS-induced nitric oxide(NO)production in RAW 264. 7 macrophages cells. Compounds 2, 6-9 exhibited moderate anti-inflammatory activities.
