A Case of Non-Hodgkin's Lymphoma in a patient with Neurofibromatosis Type 1.
- Author:
Seok Jin KIM
1
;
Jae Hong SEO
;
Sang Woo LEE
;
Eunmee HAN
;
Eung Seok LEE
;
Sang Hoon CHA
;
Bo Kyoung SEO
Author Information
1. Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. cancer@korea.ac.kr
- Publication Type:Case Report
- Keywords:
Neurofibromatosis 1;
Lymphoma;
Non-Hodgkin
- MeSH:
Aged;
Cafe-au-Lait Spots/complications/pathology;
Female;
Human;
Lung Neoplasms/*complications/pathology/radiography;
Lymphoma, Non-Hodgkin/*complications/pathology/radiography;
Neurofibromatosis 1/*complications/pathology/radiography;
Tomography, X-Ray Computed
- From:The Korean Journal of Internal Medicine
2003;18(3):202-205
- CountryRepublic of Korea
- Language:English
-
Abstract:
Neurofibromatosis type 1 is characterized by cutaneous neurofibromas and pigmented lesions of the skin called cafe au lait spots. Although neurofibromatosis type 1 represents a major risk factor for the development of malignancy, especially of nervous system tumors, malignant lymphoma rarely occurs in a patients with neurofibromatosis type 1. Recently, a 77-year-old woman with neurofibromatosis type 1 was diagnosed as non-Hodgkin's Lymphoma (diffuse large B cell). She had multiple cafe au lait spots, neurofibromas and right axillary lymph node enlargement. An abdominal CT scan demonstrated a left pelvic mass and para-aortic lymphadenopathy. Because non-Hodgkin's Lymphoma in a neurofibromatosis patient has never been reported in Korea, herein, we describe this case and include a review of the literature.
