Advances of functionalized carbon nanotubes in diagnosis and treatment of tumor
10.11665/j.issn.1000-5048.20180205
- VernacularTitle:功能化碳纳米管在肿瘤诊疗领域的研究进展
- Author:
Xiangting XU
1
;
Wei WANG
Author Information
1. 中国药科大学药剂学教研室；天然药物活性组分与药效国家重点实验室
- Publication Type:Journal Article
- Keywords:
carbon nanotube;
chemotherapy and gene therapy;
photothermal therapy;
tumor diagnosis;
advances
- From:
Journal of China Pharmaceutical University
2018;49(2):165-172
- CountryChina
- Language:Chinese
-
Abstract:
Carbon nanotubes have become a kind of superior antitumor drug and gene carrier due to their special cylindrical structure with high loading capacity and easy penetration into the cell membrane. With the gradual development of researches on carbon nanotubes, their applications in tumor photothermal therapy and diagnosis have also become current research hotspots. However, chemical inertness and aggregation of carbon nanotubes have limited their clinical application. To overcome their drawbacks, researchers would functionalize the carbon nanotubes before further researches. In this article, applications of functionalized carbon nanotubes in cancer chemotherapy and gene therapy, photothermal therapy and cancer diagnosis are summarized.
