Epidemiological analysis on a family cluster of COVID-19

Yuanying Qiu; Songqiang Wang; Xiaoli Wang; Weixia LU; Dan Qiao; Jianbin LI; Yuanyuan GU; Yan Zeng; Ying Chen; Weizhi Bai; Bianli XU; Tongwu Han

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Epidemiological analysis on a family cluster of COVID-19

VernacularTitle: 一起新型冠状病毒肺炎家庭聚集性疫情的流行病学分析
Author: Yuanying QIU ¹ ; Songqiang WANG ¹ ; Xiaoli WANG ¹ ; Weixia LU ¹ ; Dan QIAO ¹ ; Jianbin LI ¹ ; Yuanyuan GU ² ; Yan ZENG ² ; Ying CHEN ² ; Weizhi BAI ² ; Bianli XU ³ ; Tongwu HAN ¹
Author Information

1. Zhengzhou Municipal Center for Disease Control and Prevention, Zhengzhou 450007, China
2. Jinshui District Center for Disease Control and Prevention, Zhengzhou 450000, China
3. Henan Provincial Center for Disease Control and Prevention, Zhengzhou 450016, China
Publication Type:Journal Article
Keywords: COVID-19; Family cluster; Epidemiological analysis
From:Chinese Journal of Epidemiology 2020;41(4):506-509
CountryChina
Language:Chinese
Abstract: Objective:To understand the possible transmission route of a family cluster of COVID-19 in Zhengzhou and the potential infectivity of COVID-19 in incubation period, and provide scientific evidence for the timely control of infectious source and curb the spread of the epidemic.
Methods:Epidemiological investigation was conducted for a family cluster of COVID-19 (8 cases) with descriptive epidemiological method, and respiratory tract samples of the cases were collected for the nucleic acid detection of 2019-nCoV by RT-PCR.
Results:Two primary cases, which occurred on 31 January and 1 February, 2020, respectively, had a common exposure history in Wuhan. The other six family members had onsets on 30 January, 31 January, 1 February (three cases) and 3 February, 2020.
Conclusions:In this family cluster of COVID-19, six family members were infected through common family exposure to the 2 primary cases. Five secondary cases had onsets earlier than or on the same day as the primary cases, indicating that COVID-19 is contagious in incubation period, and the home isolation in the early phase of the epidemic might lead to the risk of family cluster of COVID-19.