Research progress on nucleic acid detection in Novel Coronavirus Pneumonia
10.3760/cma.j.cn114452-20200226-00128
- VernacularTitle: 新型冠状病毒肺炎核酸检测现状及研究进展
- Author:
Zhaogang DONG
1
,
2
;
Mingjin ZOU
1
,
2
;
Yi ZHANG
1
,
2
Author Information
1. Department of Clinical Laboratory, Qilu Hospital of Shandong University
2. Shandong Province Key Laboratories of Medicine and Health(Tumor Marker Translational Medicine Laboratory), Jinan 250012,China
- Publication Type:Journal Article
- Keywords:
Coronavirus;
Pneumonia, viral;
Nucleic acids;
Clinical laboratory techniques;
Quality control
- From:
Chinese Journal of Laboratory Medicine
2020;43(0):E015-E015
- CountryChina
- Language:Chinese
-
Abstract:
The prevention and control of Novel Coronavirus Pneumonia caused by Novel Coronavirus is at a critical period. Nucleic acid detection, as the definite diagnosis tool, plays an important role in rapid diagnosis, therapeutic efficacy, epidemic prevention and control. However, the disease is outbreak, and the time of nucleic acid detection in clinical application is short. So the insufficient method verification and clinical evaluation has been made. "False negative" is observed in clinical practice, and the result of nucleic acid detection is not matched with the clinical diagnosis. Therefore, it is urgent to optimize the current methods and improve detection sensitivity. Based on latest studies of Novel Coronavirus, this article reviews the current status and application prospects of nucleic acid detection. Also, this article provides references for clinicians and researchers.
