Clinical analysis of 2019 coronavirus disease (COVID-19) on one case with living-related kidney transplantation
10.3760/cma.j.cn421203-2020026-00049
- VernacularTitle: 亲属活体肾移植受者新型冠状病毒肺炎一例及临床特征分析
- Author:
Xia LU
1
,
2
,
3
,
4
;
Changsheng MING
1
,
2
,
3
,
4
;
Zhixiang WEN
1
,
2
,
3
,
4
;
Liru QIU
5
;
Shuyun XU
6
;
Tao CHEN
7
;
Qin NING
7
;
Xiaoping LUO
5
;
Zhishui CHEN
1
,
2
,
3
,
4
;
Nianqiao GONG
1
,
2
,
3
,
4
Author Information
1. Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
2. Key Laboratory of Organ Transplantation, Ministry of Education
3. NHC Key Laboratory of Organ Transplantation
4. Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan 430030, China
5. Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
6. Department of respiratory medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
7. Department of infection, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
- Publication Type:Journal Article
- Keywords:
COVID-19;
living-related kidney transplantation;
recipient;
immunosuppression;
clinical characteristics
- From:
Chinese Journal of Organ Transplantation
2020;41(0):E006-E006
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the clinical characteristics of one living-related kidney transplant recipient infected with 2019 coronavirus disease (COVID-19) .
Method:The clinical diagnosis and treatment of one relative renal transplant recipient after the occurrence of COVID-19 were analyzed retrospectively, including the course of onset, clinical manifestations, blood routine test, renal function, lung CT scan, nucleic acid detection, outpatient and inpatient therapies and outcomes.
Result:The case was diagnosed as COVID-19 (severe type) with influenza A virus infection. The clinical symptoms were gradually relieved and the lung lesions were absorbed through the treatment of reduce and stop taking immunosuppressant, antiviral therapy of abidol/oseltamivir, prevention of bacterial infection, hormone anti-inflammatory, oxygen inhalation, nutritional support and adequate rest.
Conclusion:This case present typical characteristics of COVID-19 in epidemiological investigation, clinical manifestation, examination, pulmonary imaging and etiology. After comprehensive treatment including reduce and stop immunosuppressive therapy, clinical cure was achieved. The long-term effect of COVID-19 on this immunosuppressive patient remains follow-up.