Analysis of CT features of 15 Children with 2019 novel coronavirus infection
10.3760/cma.j.issn.0578-1310.2020.0007
- VernacularTitle: 儿童新型冠状病毒感染15例CT影像特征分析
- Author:
Kai FENG
1
;
Yongxing YUN
1
;
Xianfeng WANG
2
;
Gendong YANG
1
;
Yuejie ZHENG
3
;
Chunming LIN
1
;
Lifei WANG
1
Author Information
1. Department of Radiology, the third people’s Hospital of Shenzhen, Shenzhen 518100, China
2. Department of Pediatrics, the third people’s Hospital of Shenzhen, Shenzhen 518100, China
3. Department of Respiratory Medicine, Shenzhen Children’s Hospital, Shenzhen 518038, China
- Publication Type:Journal Article
- Keywords:
Child;
2019-novel coronavirus;
Tomography, X-ray computed
- From:
Chinese Journal of Pediatrics
2020;58(0):E007-E007
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore imaging characteristics of children with 2019 novel coronavirus (2019-nCoV) infection.
Methods:A retrospective analysis was performed on clinical data and chest CT images of 15 children diagnosed with 2019-nCoV. They were admitted to the third people’s Hospital of Shenzhen from January 16 to February 6, 2020. The distribution and morphology of pulmonary lesions on chest CT images were analyzed.
Results:Among the 15 children, there were 5 males and 10 females, aged from 4 to 14 years old. Five of the 15 children were febrile and 10 were asymptomatic on first visit. The first nasal or pharyngeal swab samples in all the 15 cases were positive for 2019-nCoV nucleic acid. For their first chest CT images, 6 patients had no lesions, while 9 patients had pulmonary inflammation lesions. Seven cases of small nodular ground glass opacities and 2 cases of speckled ground glass opacities were found. After 3 to 5 days of treatment, 2019-nCoV nucleic acid in a second respiratory sample turned negative in 6 cases. Among them, chest CT images showed less lesions in 2 cases, no lesion in 3 cases, and no improvement in 1 case. Other 9 cases were still positive in a second nucleic acid test. Six patients showed similar chest CT inflammation, while 3 patients had new lesions, which were all small nodular ground glass opacities.
Conclusions:The early chest CT images of children with 2019-nCoV infection are mostly small nodular ground glass opacities. The clinical symptoms of children with 2019-nCoV infection are nonspecific. Dynamic reexamination of chest CT and nucleic acid are important.