Analysis of clinical features of 153 patients with novel coronavirus pneumonia in Chongqing
10.3760/cma.j.cn115673-20200212-00030
- VernacularTitle: 重庆地区新型冠状病毒肺炎153例临床特征分析
- Author:
Qiu WAN
1
;
Anqi SHI
;
Ting HE
;
Lixin TANG
Author Information
1. Respiratory Department of the Elderly, Chongqing Public Health Medical Center, Chongqing 400030, China
- Publication Type:Journal Article
- Keywords:
2019 novel Coronavirus;
Clinical features;
Severe disease
- From:
Chinese Journal of Clinical Infectious Diseases
2020;13(0):E008-E008
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the clinical data of 153 patients with novel coronavirus pneumonia (COVID-19) in chongqing ,and provide reference and thinking for the diagnosis and treatment.
Methods:Analyze the clinical data, laboratory examination and chest imaging characteristics of 153 COVID-19 patients in Chongqing Public Health Medical Center from January 26 to February 5, 2020. According to the relevant diagnostic criteria ,patients were divided into non-severe group(n=132) and severe group(n=21),and analyze the correlation between serum index changes and disease severity.
Results:Combined with diabetes and chronic respiratory diseases, the severity of the disease was statistically significant (χ2=11.04和6.94, P<0.05). No symptoms were found in patients with mild illness (χ2=4.09, P<0.05) .The proportion of fever and muscle soreness in the severe group was higher than that in the non-severe group (χ2=4.40 and 22.67,P<0.05).Among the concomitant symptoms, the proportion of cough and shortness of breath in the severe group was higher than that in the non-severe group (χ2=8.46 and 4.80,P<0.05).C-reactive protein and d-dimer were higher in the severe group than in the non-severe group (t=43.44 and 37.13, P<0.05), and the number of CD3+T lymphocyte cells, CD4+T lymphocyte cells and CD8+T lymphocyte cells in the severe group was lower than that in the non-severe group (Z=27.25, 20.60 and 17.36, P<0.05).Compared with the non-severe group, both lungs and the right lung lower lobe were more susceptible to involved (χ2=6.95和20.39, P<0.05) .
Conclusion:Severity of COVID-19 was associated with underlying disease, symptoms, site of involvement, C-reactive protein, d-dimer, CD3+T lymphocyte count, CD4+T lymphocyte count, and CD8+T lymphocyte count.
