Adrenocorticotropic Hormone-Secreting Esthesioneuroblastoma with Ectopic Cushing's Syndrome
10.3349/ymj.2020.61.3.257
- Author:
Young Soo CHUNG
1
;
Minkyun NA
;
Cheol Ryong KU
;
Se Hoon KIM
;
Eui Hyun KIM
Author Information
1. Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Korea. euihyunkim@yuhs.ac
- Publication Type:Case Report
- Keywords:
Cushing's disease;
ectopic ACTH syndrome, esthesioneuroblastoma;
positron emission tomography
- MeSH:
Cushing Syndrome;
Diagnosis;
Esthesioneuroblastoma, Olfactory;
Humans;
Magnetic Resonance Imaging;
Middle Aged;
Neuroimaging;
Petrosal Sinus Sampling;
Positron-Emission Tomography
- From:Yonsei Medical Journal
2020;61(3):257-261
- CountryRepublic of Korea
- Language:English
-
Abstract:
Esthesioneuroblastoma as a source of ectopic Cushing's syndrome is rare, and to the best of our knowledge, only 20 cases have been reported worldwide. A 46-year-old healthy man visited a local clinic for general weakness and hyposmia, and underwent examination with serial endocrinological workup and brain imaging. ⁶⁸Gallium-DOTA-TOC positron emission tomography scan was helpful where diagnosis of sellar MRI and inferior petrosal sinus sampling were discordant. Combined transcranial and endoscopic endonasal approach surgery was performed, and a diagnosis of esthesioneuroblastoma was given.
