Does the Oral-Anal Transit Test Correlate with Colonic Manometry Findings in Children with Refractory Constipation?
10.5223/pghn.2020.23.2.137
- Author:
Jason DRANOVE
1
;
Nathan FLEISHMAN
;
Saigopala REDDY
;
Steven TEICH
Author Information
1. Department of Pediatric Gastroenterology, Hepatology, and Nutrition, Atrium Health Levine Children's Hospital, Charlotte, NC, USA. Jason.dranove@yahoo.com
- Publication Type:Original Article
- Keywords:
Gastrointestinal dysmotility;
Fecal incontinence;
Constipation;
Colonic inertia;
Colonic manometry
- MeSH:
Child;
Colon;
Colon, Sigmoid;
Constipation;
Fecal Incontinence;
Humans;
Male;
Manometry;
Mass Screening;
Methods;
Soil
- From:Pediatric Gastroenterology, Hepatology & Nutrition
2020;23(2):137-145
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The Oral-anal Transit Test (OTT) is a simple method of obtaining information about colonic transit. We aim to assess the correlation of OTT with the neuromuscular integrity of the colon determined by colonic manometry (CM).METHODS: All patients who had OTT followed by CM were evaluated. Less than 6 of 24 markers remaining on OTT was considered normal. CM was performed per previously published guidelines. A normal CM was defined as at least one High Amplitude Propagating Contraction progressing from the most proximal sensor through the sigmoid colon.RESULTS: A total of 34 patients underwent both OTT and CM (44% male, age 4–18 years, mean 11.5 years, 97% functional constipation +/− soiling, Hirschsprung's Disease). Of normal and abnormal OTT patients, 85.7% (6/7) and 18.5% (5/27) respectively had normal CM. When all markers progressed to at least the sigmoid colon, this was 100% predictive against colonic inertia. Greater than 50% of patients with manometric isolated sigmoid dysfunction had markers proximal to the recto-sigmoid.CONCLUSION: OTT and CM are both valuable studies that assess different aspects of colonic function. OTT can be used as a screening test to rule out colonic inertia. However, the most proximal extent of remaining markers does not predict the anatomical extent of the manometric abnormality, particularly in isolated sigmoid dysfunction.
