Cow's Milk-Related Symptom Score in Presumed Healthy Polish Infants Aged 0–6 Months
10.5223/pghn.2020.23.2.154
- Author:
Karolina BIGORAJSKA
1
;
Zuzanna FILIPIAK
;
Paulina WINIARSKA
;
Anita ADAMIEC
;
Bogumiła TRENT
;
Yvan VANDENPLAS
;
Marek RUSZCZYŃSKI
;
Hania SZAJEWSKA
Author Information
1. The Student's Scientific Group of the Department of Paediatrics, The Medical University of Warsaw, Warsaw, Poland.
- Publication Type:Original Article
- Keywords:
Infant;
Milk;
Food allergy;
Food hypersensitivity
- MeSH:
Child;
Chronic Disease;
Cross-Sectional Studies;
Crying;
Dietary Supplements;
Food Hypersensitivity;
Humans;
Hypersensitivity;
Infant;
Milk;
Parents;
Poland;
Skin
- From:Pediatric Gastroenterology, Hepatology & Nutrition
2020;23(2):154-162
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The Cow's Milk-related Symptom Score (CoMiSS™), which considers crying, regurgitation, stools, skin and respiratory symptoms, was developed as an awareness tool for evaluating cow's milk-related symptoms. The scoring ranges from 0 to 33. A score ≥12 was proposed as being likely cow's milk-related and suggestive of allergy to cow's milk. This study aimed to determine the age-related CoMiSS™ values in presumed healthy infants in Poland.METHODS: This was a cross-sectional study conducted in well-child clinics in two locations. Parents of the presumed healthy infants aged ≤6 months were approached during a routine checkup/vaccination visit. The exclusion criteria were as follows: presence of acute or chronic diseases, preterm delivery, treatment with therapeutic formula, and use of any food supplements (except vitamins) or medications.RESULTS: Data from 226 infants were obtained (median age [Q1–Q3], 4 months [3–4]). The overall median (Q1–Q3) and mean (standard deviation) CoMiSS™ values were 4 (2–7) and 4.7 (3.5), respectively. The 95th percentile was 11. Scores on some, albeit not all, components of the CoMiSS™ significantly differed between age groups (crying, stools) or feeding type groups (stools and skin symptoms). Eleven children (4.9%) scored ≥12.CONCLUSION: This study adds to earlier age-related CoMiSS™ data by providing CoMiSS™ values in presumed healthy infants in Poland.