The effect of ginger and metoclopramide in the prevention of nausea and vomiting during and after surgery in cesarean section under spinal anesthesia
10.5468/ogs.2020.63.2.173
- Author:
Hamideh PAKNIAT
1
;
Fatemeh LALOOHA
;
Farideh MOVAHED
;
Aynaz BOOSTAN
;
Marzieh Beigom KHEZRI
;
Caleb HEDBERG
;
Mohammad Ali HOSSEINI
Author Information
1. Department of Obstetrics and Gynecology, Qazvin University of Medical Sciences, Qazvin, Iran. Lalooha44@yahoo.com
- Publication Type:Original Article
- Keywords:
Cesarean section;
Spinal anesthesia;
Metoclopramide;
Ginger
- From:Obstetrics & Gynecology Science
2020;63(2):173-180
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: Postoperative nausea and vomiting is one of the most common side effects after anesthesia in surgeries, such as cesarean section. This study aimed to investigate the effect of ginger and metoclopramide in the prevention of nausea and vomiting during and after cesarean section.METHODS: This clinical trial was conducted on 180 patients aged 18–40 years who underwent cesarean section under spinal anesthesia. The first group received 10 mg of metoclopramide via intravenous injection (metoclopramide group), and the second group received 1 g of oral ginger (ginger group) half an hour before spinal anesthesia. The frequency and severity of nausea and vomiting during surgery and at 2, 6, 12, and 24 hours postoperatively were compared in both groups. To analyze the results, the t-test, chi-square test, and Mann-Whitney test were used.RESULTS: There was no significant difference in the frequency of nausea and vomiting between the 2 groups during operation, 2 hours and 6 hours after surgery (P=0.182, 0.444 and 0.563 respectively). The severity of nausea and vomiting was also similar in the 2 groups (P=0.487 and 0.652 respectively); however, the metoclopramide group had a lower systolic blood pressure (P<0.001; df=2.176; f=18.66) and mean arterial pressure (P<0.001; df=2.176; f=6.36) than the ginger group.CONCLUSION: The results revealed that ginger reduced nausea and vomiting to the same extent as metoclopramide in patients undergoing cesarean section.TRIAL REGISTRATION: Iranian Center for Clinical Trials Identifier: IRCT201611028611N3
