The Effect of Combination Therapy of Kanamycin Plus Talampicillin for Uncomplicated Male Gonorrhea.
- Author:
Kwang Ho CHOI
;
In Sub YANG
;
Jae Hong KIM
;
Joong Hwan KIM
- Publication Type:Original Article
- Keywords:
Combination therapy;
Kanamycin;
Talampicillin;
Gonorrhea
- MeSH:
General Practice;
Gonorrhea*;
Humans;
Kanamycin*;
Korea;
Male*;
Probenecid;
Talampicillin*
- From:Korean Journal of Dermatology
1985;23(4):462-467
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The treatment of gonorrhea caused by beta-strains of N. gonorrhoeae is quite different from that of non-beta-strains, but it is not always possible in general practice to take cultures of gonococci to detect p-lactamase producing organisms. Therefore treatment regimens commonly used for gonorrhoea should be effective against both PPNG non-PPNG strains. Eighty-seven male uncomplicated gonorrheal patients were treated with intramuscular kanarnycin 2gm in combilnation with talampicillin 2. 5 gm plus probenecid 1grn orally. Sixty-seven patients were followed up. All patients recovered. Ten patients among sixty-seven patients had PPNG. A regimen of intramuscular kanamycin 2 gm, talampicillin 2. 5 gm plus probenecid 1 0 gm orally seems to be one of the most cost effective regimens in Korea.
