Changes in ventricular repolarization after balloon valvuloplasty in patients with pulmonary stenosis.
10.4070/kcj.2001.31.3.341
- Author:
Jae Kon KO
;
So Young YOON
;
Young Hwee KIM
;
In Sook PARK
- Publication Type:Original Article
- Keywords:
Mechanoelectrical feedback
- MeSH:
Action Potentials;
Balloon Valvuloplasty*;
Blood Pressure;
Humans;
Pulmonary Valve Stenosis*
- From:Korean Circulation Journal
2001;31(3):341-346
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Alterations in ventricular loading conditions lead to changes in action potential duration via mechanoelectrical feedback. A decrease in load immediately leads to prolongation of repolarization. QT interval and QT dispersion were measured to determine the long-term effect of changes in ventricular systolic load on the ventricular repolarization. METHOD: Corrected QT interval and QT dispersion were measured in 26 patients before and 3-6 months after valvuloplasty for pulmonary stenosis. To determine the effect of ventricular load on ventricular repolarization, patients were divided in 2 groups; Group 1 was those patients with a greater than 30 mmHg and Group 2 was those patients with a less than 30 mmHg decrease in right ventricular systolic pressure. RESULTS: Corrected QT interval (412.6+/-14.5 msec vs 426.4+/-16.8 msec, p < 0.05) and QT dispersion (35.0+/-7.3 msec vs 45.7+/-14..1 msec, p < 0.05)were increased significantly only in Group 1 after vlavuloplasty. CONCLUSION: It suggested that mechanoelectrical interactions are operative for long duration in humans that changes in ventricular load after successful pulmonary valvuloplasty showed long-term effect on the ventricular repolarization.
